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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dae597d14fc39d4b34fe747bf7afe2533f7f05afa2203c5f78b26c9cea0138e' 
  AND token = 'qotPXJ9c2Ikr4MiSha6d+/R5MXopne9+HznMNyElvtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}