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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c45dbdf7c1e4cfc39a2d1efa57d0d657f535d8eda1e1dea19068c0b48747d4df' 
  AND token = 'B88bKFuuhKxmvY8oYA/7s+8Q4PlKdGYxiNoiM1aIWDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}