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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3be4acbb92a8c98072b32f1da7fb6be4bc35beafba2aab44283224ff560471' 
  AND token = '+2XkbaFx5fOG+2VME/RcSjaPPbe1M8rnZiqhskpHTJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}