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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f21f3955dc518f8cc93d4fa055c99e8704a28e0a0b511e6d615bf8685c76949' 
  AND token = 'fn4lasvYRy7B30Lw8UrQxYLw9FB1wVoqadujOMA3oXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}