SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edfd167913aa51cd871c6ee8dc5476948b527f95df6182d445736fc54d4d875b' 
  AND token = 'w9M0kGOH3DRO33g8twuMaLDDb+1ZhCiGS7qhXJtA7JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}