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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e80916a884760773650f9c586beb571e6fe39db2213c581da177ce33aba8c13' 
  AND token = 'P7yejhOJkY8MwGmivbvETt/6/aCHDpfphY+lWcL9i80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}