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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943fa23a5ecd0dcf7e058c1ec29dd04302c14a0a38ab0db813286f4f318f342d' 
  AND token = 'IcRJLq3dVgpMTm9bEiUkS0Uk30GQ9DKeRihGQ7ry56s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}