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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353236ff8ed53ac79c6444f78cbac5869aaf578b185b7aa30a0f4fe45c1aada0' 
  AND token = 'n2Xi5TzS8E5ZOEqDTzsUtsF9PZ+Q4ZIqvIIhq+FnwPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}