SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6345e51c23c04e58a9c42ad8658448325a356b8b8c61985367b3b1bd0f7513' 
  AND token = 'r2DBSxWas8zPi5oT0pr4PkvGhPL4g5fNBtJMRjuvKbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}