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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6db8ca098ec6407fcb996e9cfd03f0c98a1b7c45312b00b2f57342a6c12b75f' 
  AND token = '+4eRR0/dzkyH9TYe+iTFwI9x+slYeN25sncT3j075p8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}