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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc3ff3de9b0a328e1b908fa5646c4c6b7d037a60bdc0c72aa81a03eaded24a5f' 
  AND token = 'aocs6p2lArntjvX4R74YKCi4TFzKd+91BPixxV7IKts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}