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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47b810bad661e7e423ab6fd5775a2e38ad185ef9416e23b76efed0032c48c80f' 
  AND token = '+txSIXlDX//cpJ3Q3PHvv/xP9XBM7sx2pPzR2l4Ep3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}