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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04dba38e0d1f1a97363ee7eb899ea7ee2738162a1c2bcc4e934926a366d103b0' 
  AND token = 'ZGDbQWV7kxw8dNJD6RMU3uZXa75UkcN5QrF/Mq6R0so=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}