SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f530b2551b7759d3f66a4e51218c308843c04c3553474c7b06260736d9e6a103' 
  AND token = 'I2M+V5miWPJFWK4k6qpE/zsVm4w6gUTe9CNrd2w0VUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}