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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195124c20956a290892b5e30d213cc33bea6af2c45a16a01026dccacff67e38a' 
  AND token = 'qV3NFHhZYAlhUp0L0jCaI9+3PhuMPHvZs0hVc5cxg7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}