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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eca497b5211b8f9f8b2465cb5c2b537a7cfd94d6b1d63346b8630f39b87c1ab9' 
  AND token = '0EC3+KrMiFZXSx15/jLyPLQMQZ6rWn+y06WvkMidwbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}