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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2822ea57f5f677e766c374476235919ee1da74b3852d1b94fd1dbbac3c181e8a' 
  AND token = 'JV2VhOyUgI21bUTSTGTksh0SqJvEVaiXsbscO7k2V2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}