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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22bb984036fce936dbc80f15fd869aa7f316997e0b7bc28e10f54f03c6a4d82' 
  AND token = 'rQdiJ6ib/H0HiTDuExrX1d5R7ekpvKJ0++9Vyz9Ti+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}