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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52e2f255e7817e154c704faa3ef11ba8e48e516c4b60c1f76e18d4ffc32e43f' 
  AND token = '+lzkPlCFMhCU+J7lAyiQTGF1hnX3ayyxksmCGMFKug4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}