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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a2e31ddabf70a8a4e415aa7d71bad493cf4fb0ff3586d5c4f33acb148af272' 
  AND token = 'edZ6TJf8veydBu33d6aVHnFFaF1jtt5v778CdF/76eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}