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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c7e355e3749ed7d33189d33583f9778526fd30c669aa3499712a466f17a0bf' 
  AND token = 'bW+q1CZdGP3iBCQ/TdxNQsBox1nUsRpE3QsqN+47mkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}