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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9951c1b32a880be9def65fbd34e3cba91719b5642ab5ee7d2190a9a41bb038c' 
  AND token = 'LJy6KUie5s0b5mvIrd1XWm0fMdjhuwlWz1bO5NYeJAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}