SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3acf1c9f9d3e64685d950de348879b32b49c754ebe6fe4c443e9f56ab877471e' 
  AND token = 'dEspTO+PVaflcD61F8V+uxrtngRaybLfXdMu97bz4xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}