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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7573c8e402baa622cb503de90f0bc0936d1290e31de284700690090feca6c536' 
  AND token = 'eqhiM9GWbn+uPWbZH1ulc1n7tghaZM/YMsidSD5c3oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}