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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d3e58bcc41e2ec143297806ed32a5c649d061ff01a4b29270d867987f51aff' 
  AND token = '9Xs1ysSzh/5V47ue/MLN3cgDH2GWBZHPm5tknAa6B9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}