SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '044786a0d653ae83cd6e0f9cfdb4d9420961c32fc8be6244a4d57cce706c9c05' 
  AND token = '+Sg6MtmoI5G90ngAdDpmRqcoaX/UgIK/RcDnnq3i4PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}