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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589564d2de7ed37d120c47e1b9a60b3566cccd231503cbd51b8d2e50a595542d' 
  AND token = '7UY+L7OrRz+2RruHd+MqDTf+ozC0JCDvGvV/DJ8dRt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}