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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b50f2c671add792b50c124fb08d9a4c496262817cdf8ad37fc18aa59d0da45b8' 
  AND token = 'N4tUYwukQPGZByXGwR1PLbRL53EQw2D/ne8yvnhd2Ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}