SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73e0cdc2f58160d5af16eca9bf46d506fe532bb336c53cc09df2540b5dc4f61f' 
  AND token = 'XcpYXruTvmdYnrjrVCpdVi6+Q7ARlzLCyfa3EI80Ej4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}