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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4de571f7390aa3fb5f5729d1f33ae41f4a5b8953c8c26b1d335f5d0f2bac671' 
  AND token = '6JpEUdISWrMgGcGfhjsmOn2al11CyMv9XDf0OWARfbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}