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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b6718a5a3b69019ddb3ac1167476ac69f426a88c95ca7ca2baf685c34ebd43' 
  AND token = 'CAsy8oZvOTvCn1LKYKCHxjHPXDbjZk8W4aYy79BhxO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}