SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '158f4d38a9bd0f37bd55d08fc18284c5b58109c8c6e96d406a2a3cbd4813d6e8' 
  AND token = 'HINPUEzEbAwnRBZZBtXukO+UJ84RJayN88WhRL9cobc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}