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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a6c1af3b332df3b95980ef6b4d4e6f1b92d6906b63cac4e8f22df5bfc3cd994' 
  AND token = '6JJNZ8ddSmato2U9JOrx/eumYRsPx1dJ5/PLxDGXZBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}