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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a08623a3477b045adead93f427adc2b9ae43451535301298fa93b0f02a77b2' 
  AND token = '6EKkw8FDMmKhESrnQQrZ0rBO/6whdx8zPoGcvmE1fmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}