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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44967c7f829ba5d8deb7269397ffb234ddd11d0aae4bfa5751a6da80058c0364' 
  AND token = 'owrDn+p5mFWdPoNPx/xMf7riEZkKl6lkDmAkV6QBwts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}