SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c01a36979cf409d5e47174c89da97e97bc8ff6e8bbb19562bf2007e9c509d883' 
  AND token = 'dhzc9tWH+yv46OXoU4IQqQLHs0X/uG/bEK71nFcbLR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}