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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa795a75b308f166f66312273cbd435199eb79bcd2ead0c249f3bce0f63a1602' 
  AND token = '2DZqphFyypbtTRN5G3jL3KTXYr0h+ps4q4xRORvuSRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}