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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4be07ab2879530dbc650dc9f2c3d62c7790d180eab641680610a4eb13c6a37e' 
  AND token = '5wbhR4yWRsBif0VQS/rB/5Elsmb+wYeQDtqyPiKb6lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}