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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f01460b990e9695b8fbe7d186d70e53b4cc04af08fd4832b06dd27dbcae4e69' 
  AND token = '6pPYtduL63hIu+skgo1zfhHcaJutMhpM23FYPUPHvAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}