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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ca08d47078d4cd1fd6467ddd0dbc183d0447d8f1648f98f380295b934b7cb03' 
  AND token = 'jQ90r5+LlGY6uv2Rswl3NCIHzKDfz1zu5ymymZ6mGmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}