SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e7557f6dec479e5f1f4ad33bddf99253a2e23fc0d9bd9bf375412d874f52c1' 
  AND token = 'mlrrUHNyn4ahx/77mTJ6YGgnNpO2u3GeKeueWVZudPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}