SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1d62328161f945a0655316bba150a546f8e6d952c6d0921bc176f5918b91fa7' 
  AND token = 'zpvEaAyTBtzzei42QcP2tT+VWakAFfFFjfJh9gmOl2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}