SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1544043d40c2821243cbefde46fbc95cc5ec95cf162edc4071f3d9e856563fe1' 
  AND token = '6kQ7lTw2c1UHju9RxLuRR+QrGBN39WWzGvzmWwDRo14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}