SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7585153e262beb4c61e5a287b9c80680698686e7e80001804a06ec8983d25650' 
  AND token = 'GlB7mZGdRq+ttkfrNWkbMgZGkJHZbcQWfVV+sp4iYBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}