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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bfb8f1e0a2505af71ad6852f6508af804a53e81c6756f49b638a18572f3798f' 
  AND token = 'W2d94rxynq8Gg6lC1FIQPppORm9ZpzgfRAm8cAv0SrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}