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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '190df4e3a891214621a2fb0daf7007b3cefb02de539b7cf22ed45b6178cca7c6' 
  AND token = 'scju6znwE7M+k9rfe4zuvVx1ISF5g5663hF89rD8n0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}