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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc08ac2728063742f8150aa4cbe66eb16e47c8c3c6097420f821e939e4a769e3' 
  AND token = '81Otsx3g6wXbpEMlqeGMwQx0uOKrsBEyLRxH5AHe994=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}