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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eef579ed82d366188e2d12156e6796a6877526187b2e81f65a6677c89010c9d5' 
  AND token = '4Gvv8uH8Se6Gv+gZMwAk0+IUtqkhZqPOuSh+H8cVJ40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}