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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8fe4ba08f58ecbef6c1a8cf8953951ae68fa269f629e07ab54baeb857072f21' 
  AND token = 'mQte7G2PHf41rgE7Ey2FWuQCkb10fQxRbB1SnXNxh/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}