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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377a07405642a5ec73577021b46338ccb7d351596ac12396d9da4b14cd2ba77a' 
  AND token = '0WzsNDBCf+nOUKncUya5YzrEmoPvCxZmPzifIfAirtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}